i8彩票注册

广东省微〓生物菌种保藏中心    副教授

  分子酶【学与酶工程

1. Zhou X, Xu Z, He J, Li Y, Pan C, Wang C, Deng M, Zhu H*. A myxobacterial LPMO10 has oxidizing cellulose activity for promoting biomass enzymatic saccharigication of agricultural crop straws. Bioresour. Technol. 2020, 318:124217.

2. Zhou X, Zhu H*. Current understanding of substrate specificity and regioselectivity of LPMOs, Bioresour. Bioprocess. 2020, 7(1): 11.

3. Zhou X, Qi X, Huang H, Zhu H*. Sequence and structural analysis of AA9 and AA10 LPMOs: an insight into the basis of substrate specificity and regioselectivity, Int. J. Mol. Sci. 2019, 20(18): 4594-4608.

4. Zhang H, Fei R, Xue B, Yu S, Zhang Z, Zhong S, Gao Y, Zhou X*. Pnserpin:a novel serine protease inhibitor from extremophile pyrobaculum neutrophilum, Int. J. Mol. Sci. 2017, 18(1): 113-126.

5. Zhou X, Yu S, Su J, Sun L *. Computational study on new natural compound inhibitors of pyruvate dehydrogenase kinases. Int. J. Mol. Sci. 2016, 17(3):340-352.

6. Zhang W, Su J, Xu H, Yu S, Liu Y, Zhang Y, Sun L, Yue Y*, Zhou X*. Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells, Plos One, 2017, 12(6): e0179672.

7. Zhou X, Gao L, Yang G, Liu D, Bai A, Li B, Deng Z, Feng Y*. Design of hyperthermophilic lipase chimeras by key motif-directed recombination, Chembiochem, 2015, 16(3): 455-462.

8. Yu S, Zhou X, Li F, Xu C, Zheng F, Li J, Zhao H, Dai Y, Liu S, Feng Y*. Microbial transformation of ginsenoside Rb1, Re and Rg1 and its contribution to the improved anti-inflammatory activity of ginseng. Sci. Rep. 2017.7(1):138-147.

9.  Fei R, Zhang H, Zhong S, Xue B, Gao Y, Zhou X*. Anti-inflammatory activity of a thermophilic serine protease inhibitor from extremophile Pyrobaculum neutrophilum. Eur. J. Inflamm. 2017,15(3):143-151.

10. Zhou X, Han W, Zheng B, Feng Y*. Insight into substrate preference of two chimeric esterases by combining experiment and molecular simulation. Chem. Res. Chin. Univ. 2013, 29(3): 533-537.

11. Zhou X, Wang H, Zhang Y, Gao L, Feng Y*. Alteration of substrate specificities of thermophilic alpha/beta hydrolases through domain swapping and domain interface optimization. Acta. Biochim. Biophys. Sin. 2012, 44(12): 965-973.

1. 国家自然科学基金青年基金，基于协同进化原则的蛋白质结〖构域重组策略及其在构※建超嗜热脂肪酶中的应用（项目编号：31400681）

2. 吉林省⊙自然科学基金，肝癌细胞丙酮酸激酶双重调节糖代谢机制及靶向药物的→筛选（项目编号：20180101307JC）

3.  吉林省科技厅青年科○研基金，蛋白质结构域︾重组构建新型热稳定丝氨¤酸蛋白酶抑制剂 （项目编号： 20160520142JH）

4. 吉林■省卫生计生青年科研课题，嗜热丝氨酸蛋白酶ω抑制剂Pnserpin 的结构功能及抗炎活性研究（项目编号： 2015Q016）