八一彩票官方网站

<i id='Wkgko3'></i>

_{<blockquote id='Wkgko3'><q id='Wkgko3'><noscript id='Wkgko3'></noscript><dt id='Wkgko3'></dt></q></blockquote><noframes id='Wkgko3'><i id='Wkgko3'></i>}

副高级

肖春

食用菌研究发展中心副研究员

研究领域：

食药用菌多糖降血糖功能机【制研究。

代表论著：
1. Chun Xiao^#, Chunwei Jiao^#, Yizhen Xie, Linhui Ye, Qianqing Li, Qingping Wu^*. Grifola frondosa GF5000 improves insulin resistance by modulation the composition of gut microbiota in diabetic rats. J Funct Foods, 2021, 77:104313.

2. Chun Xiao^#, Qingping Wu^#*, Yizhen Xie, Jianbin Tan, Yinrun Ding, LijuanBai. Hypoglycemic mechanisms of Ganoderma lucidum polysaccharides F31 in db/db mice via RNA-seq and iTRAQ. Food Funct, 2018, 9: 6496-6508.

3. Chun Xiao^#, Qingping Wu^#*, Jumei Zhang, Yizhen Xie, Jianbin Tan. Antidiabetic activity of Ganoderma lucidum polysaccharides F31 down-regulated hepatic glucose regulatory enzymes in diabetic mice. J Ethnopharmacol, 2017, 196: 47-57.

4. Chun Xiao^#, Qingping Wu^#*, Yizhen Xie, Jumei Zhang, Jianbin Tan. Hypoglycemic effects of Grifola frondosa (Maitake) polysaccharides F2 and F3 through improvement of insulin resistance in diabetic rats. Food Funct, 2015, 6: 3567-3575.

5. Chun Xiao^#, Qingping Wu^#*, Wen Cai, Jianbin Tan, Xiaobing Yang, Jumei Zhang. Hypoglycemic effect of Ganoderma lucidum polysaccharides in type 2 diabetic mice. Arch Pharm Res, 2012, 35:1793-1801.

6. Chun Xiao, Qingping Wu^*, Jianbin Tan, Wen Cai, Xiaobing Yang, Jumei Zhang. Inhibitory effects on alpha-glucosidase and hypoglycemic effects of the crude polysaccharides isolated from 11 edible fungi. J Med Plants Res, 2011, 5: 6963-6967.

7. 肖春, 吴清平^*, 蔡玟, 谭剑斌, 黄俊明, 杨小兵. 灵芝粗多糖对糖尿病小鼠的降血糖作用. 中国食用菌，2011，03：37-39.

8. Yinrun Ding, Chun Xiao, Qingping Wu^*, Yizhen Xie. The mechanisms underlying the hypolipidaemic effects of Grifola frondosa in the liver of rats, Front Microbiol, 2016:1186.

9.吴清平^*, 肖春, 杨小兵, 张菊梅. 食(药)用菌多糖类物∞质降血糖作用及其机理研究进展. 食用菌学报，2009, 16：80-86.

主持项目(省部级以上):

1.广东省自然科学基金项目，面上项目，灵芝多糖F31调节GK表达改善肝脏糖代谢紊乱的分子机制研究，2021-01 至 2023-12，已立项；

2.广东省自然科学基金，博士启动，灵芝活性多糖F31的一级结构解析及其调控肝脏糖异生信号转导的研究（2015A030310001）,2015-08 至 2018-08，10万元，已结题；

3.广东省省级产业技术研究与开发计划项目，食药用菌降血糖功能新产品的研制及产业化示范，2012-08 至 2015-07，100万，已结题。

授权专利:

1.吴清平, 肖春, 谢意珍, 杨小兵, 李森柱. Process for Preparation of a Grifola frondosa Polysaccharides F2 and Its Hypoglycemic Activity, 2018-12-18，美国，US10155822B2.

2.吴清平, 肖春, 杨小兵, 谢意珍, 李森柱. 灰树花多糖F2的制备方法及其降血糖ξ功能，2016-08-17, 中国，ZL201310733480.8.

3.吴清平, 肖春, 杨小兵, 谢意珍, 李森柱. 灵芝多糖F31的制备方法及其降血糖功能，2013-11-13，中国，ZL201210056087.5.